National Repository :: Browsing by Author "Chepukosi, Kennedy W."

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Manganese exacerbated chronic khat-induced neurological deficits, inflammation and organ toxicity in a mouse model
(Springer, 2021-12-01) Chepukosi, Kennedy W.; Nyariki, James N.; Jillani, Ngalla E.; Okanya, Patrick W.; Isaac, Alfred Orina
This study sought to determine whether chronic exposure to khat (Catha Edulis, Forsk) increases the vulnerability to the toxic effects of manganese (Mn2+), when co-exposed.Three (3)-week-old forty (40) Swiss albino mice were randomly divided into four groups (n = 10). The various groups received khat and manganese separately or both. The experiment was conducted for 132 days to mimic chronic exposure to khat, with manganese administration in the last twelve days.