Browsing by Author "Isaac, Alfred Orina"
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Publication Manganese exacerbated chronic khat-induced neurological deficits, inflammation and organ toxicity in a mouse model(Springer, 2021-12-01) Chepukosi, Kennedy W.; Nyariki, James N.; Jillani, Ngalla E.; Okanya, Patrick W.; Isaac, Alfred OrinaThis study sought to determine whether chronic exposure to khat (Catha Edulis, Forsk) increases the vulnerability to the toxic effects of manganese (Mn2+), when co-exposed.Three (3)-week-old forty (40) Swiss albino mice were randomly divided into four groups (nā=ā10). The various groups received khat and manganese separately or both. The experiment was conducted for 132 days to mimic chronic exposure to khat, with manganese administration in the last twelve days.