Browsing by Author "Prasanna, Boddupalli Maruthi"

Now showing 1 - 1 of 1
  • Publication
    Publication
    Maize Lethal Necrosis disease: review of molecular and genetic resistance mechanisms, socio-economic impacts, and mitigation strategies in sub-Saharan Africa
    (springer, 2022-11-23) Biswal, Akshaya Kumar; Alakonya, Amos Emitati; Mottaleb, Khondokar Abdul; Hearne, Sarah J.; Sonder, Kai; Molnar, Terence Luke; Jones, Alan M.; Pixley, Kevin Vail; Prasanna, Boddupalli Maruthi
    Maize lethal necrosis (MLN) disease is a significant constraint for maize producers in sub-Saharan Africa (SSA). The disease decimates the maize crop, in some cases, causing total crop failure with far-reaching impacts on regional food security. In this review, we analyze the impacts of MLN in Africa, finding that resource-poor farmers and consumers are the most vulnerable populations. We examine the molecular mechanism of MLN virus transmission, role of vectors and host plant resistance identifying a range of potential opportunities for genetic and phytosanitary interventions to control MLN. We discuss the likely exacerbating effects of climate change on the MLN menace and describe a sobering example of negative genetic association between tolerance to heat/drought and susceptibility to viral infection. We also review role of microRNAs in host plant response to MLN causing viruses as well as heat/drought stress that can be carefully engineered to develop resistant varieties using novel molecular techniques.