Preclinical efficacy testing of three antivenoms against Naja ashei venom-induced lethality

dc.contributor.author	Mitchel Otieno Okumu Paul Gichohi Mbuthia, James Mucunu Mbaria, Vincent Odongo Madadi, Joseph Kangangi Gikunju, Kenneth Narotso Maloba, Francis Okumu Ochola, Joseph Gichuki Nderitu
dc.date.accessioned	2025-07-17T08:41:26Z
dc.date.issued	2022-06
dc.description.abstract	This study aimed to determine the efficacy of Inoserp, Vins bioproducts, and South African Institute of Medical Research (SAIMR) polyvalent antivenoms in neutralizing Naja ashei venom-induced lethality in mice. The neutralization efficacy of the antivenoms were expressed as effective dose, median effective ratio, potency, normalized potency, volume, and the number of vials of antivenom required to neutralize 100 mg of Naja ashei venom (NAV).
dc.description.sponsorship	NRF
dc.identifier.uri	https://doi.org/10.1016/j.toxcx.2022.100124
dc.identifier.uri	https://repository.nrf.go.ke/handle/123456789/1432
dc.language.iso	en
dc.publisher	ELSEVIER
dc.relation.ispartofseries	Volume 14, June 2022, 100124
dc.subject	SnakebiteNaja asheiAntivenomsNeutralizationPotency
dc.title	Preclinical efficacy testing of three antivenoms against Naja ashei venom-induced lethality
dc.type	Article
dspace.entity.type	Publication