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Manganese exacerbated chronic khat-induced neurological deficits, inflammation and organ toxicity in a mouse model

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dc.contributor.authorChepukosi, Kennedy W.
dc.contributor.authorNyariki, James N.
dc.contributor.authorJillani, Ngalla E.
dc.contributor.authorOkanya, Patrick W.
dc.contributor.authorIsaac, Alfred Orina
dc.date.accessioned2024-07-03T08:46:58Z
dc.date.issued2021-12-01
dc.description.abstractThis study sought to determine whether chronic exposure to khat (Catha Edulis, Forsk) increases the vulnerability to the toxic effects of manganese (Mn2+), when co-exposed.Three (3)-week-old forty (40) Swiss albino mice were randomly divided into four groups (nā€‰=ā€‰10). The various groups received khat and manganese separately or both. The experiment was conducted for 132 days to mimic chronic exposure to khat, with manganese administration in the last twelve days.
dc.description.sponsorshipNACOSTI
dc.identifier.citationChepukosi, K. W., Nyariki, J. N., Jillani, N. E., Okanya, P. W., & Isaac, A. O. (2021). Manganese exacerbated chronic khat-induced neurological deficits, inflammation and organ toxicity in a mouse model. Toxicology and Environmental Health Sciences, 13(4), 337-350.
dc.identifier.issn2233-7784
dc.identifier.urihttps://link.springer.com/article/10.1007/s13530-021-00091-9#citeas
dc.identifier.urihttps://repository.nrf.go.ke/handle/123456789/1087
dc.language.isoen
dc.publisherSpringer
dc.subjectCatha edulis
dc.subjectPollution
dc.subjectMetal toxicity
dc.titleManganese exacerbated chronic khat-induced neurological deficits, inflammation and organ toxicity in a mouse model
dc.typeArticle
dspace.entity.typePublication

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