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Bioprospecting for Phytochemical Repellents and bio-pesticides of the Jigger Flea Tunga penetrans from the Western Kenya Flora.
(WIPO International Publication, 2022-03-03) Maurice V. Omolo, Paul K. Tarus, Joseph Owino, Regina Bwire, Vitman M. Wafula, Judith V. Adhiambo, Regina J. Cheptum, Vincent C. Terer, Anderson Misati, James Nonoh, John Muoma, Dennis Ochieno and Consolata Ngala
Discloses a composition comprising for treating jigger infestation, comprising Nicotine and related compounds present in Nicotiana tobaccum as bio-pesticides and antitungiasis of the jigger flea, Tunga penetrans. A single application of 10% formulation of Nicotine, nornicotine, Anabasine, Anatabine, Continine and myosmine in the ratio of 85: 2: 4: 7: 1: 1 respectively in petroleum jelly base of 90% and lemon Eucalyptus oil of 1 g on a jigger (6) infested victim's feet (6) gives 100% pesticide activity within 5-7 days as demonstrated by recovered foot (2B) and jigger scars (8). The said bio-chemicals, alone or in combination with one another and/ or other natural or synthetic pesticides exhibit activity against the jigger flea among other blood feeding insect & arachnid pests of humans and animals. Also discloses a method of formulating the bio-pesticide composition consisting of Nicotine and other biomolecules extracts from Nicotiana tobaccum.